Potassium-sparing diuretics

Topic: Pharmacology

Weak diuretics that increase sodium excretion in the distal nephron while retaining potassium: aldosterone antagonists (spironolactone, eplerenone) and epithelial sodium channel blockers (amiloride, triamterene). They are used in heart failure, ascites from cirrhosis, primary hyperaldosteronism and resistant hypertension. The main danger is hyperkalemia, more likely with ACE inhibitors, ARBs or kidney failure; spironolactone can cause gynecomastia. Monitor potassium and kidney function, and teach the client to avoid potassium supplements and potassium-based salt substitutes.

Also known as:

Aldosterone antagonists, Mineralocorticoid receptor antagonists, Spironolactone

In Turkish:

Potasyum tutucu diüretikler