Proton pump inhibitors

Topic: Pharmacology

Drugs that block the final step of acid secretion in the gastric parietal cells (e.g., omeprazole, pantoprazole); used for gastroesophageal reflux, peptic ulcer, H. pylori eradication with antibiotics, stress ulcer prevention and stomach protection during NSAID therapy. Oral forms work best taken before breakfast. Use, especially long-term, is linked to Clostridioides difficile infection, pneumonia, low magnesium, vitamin B12 deficiency and fractures, so the continued need should be reviewed. Teach the client to swallow delayed-release forms whole and to report black stools.

Also known as:
PPIs, PPI

What does Proton pump inhibitors mean?

Proton pump inhibitors is part of the Pharmacology topic in nursing. Students meet it in class, on clinical placements and while preparing for exams.

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