Serotonin syndrome

Topic: Pharmacology

A potentially life-threatening reaction to serotonergic drugs (such as SSRIs, SNRIs, MAO inhibitors, tramadol and triptans), most often when they are combined but also with one drug alone, especially when it is started or its dose is increased. Signs include agitation or confusion, tachycardia, hyperthermia, sweating, diarrhea, tremor, clonus and hyperreflexia. Hold the suspected drug, notify the prescriber and monitor vital signs and temperature closely.

Also known as:
Serotonin toxicity

What does Serotonin syndrome mean?

Serotonin syndrome is part of the Pharmacology topic in nursing. Students meet it in class, on clinical placements and while preparing for exams.

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