GLP-1 receptor agonists

Topic: Pharmacology

Injectable or oral drugs that mimic the gut hormone GLP-1 (e.g., liraglutide, semaglutide): they increase glucose-dependent insulin release, suppress glucagon, slow gastric emptying and reduce appetite. They treat type 2 diabetes, and some treat obesity. Nausea, vomiting and diarrhea are common; hypoglycemia is unlikely unless combined with insulin or a sulfonylurea. They are not used with a personal or family history of medullary thyroid cancer or MEN 2. Teach the client to report severe abdominal pain (pancreatitis) or persistent vomiting and to tell the anesthesia team before surgery.

Also known as:

GLP-1 agonists, Incretin mimetics

In Turkish:

GLP-1 reseptör agonistleri