Hyperosmolar hyperglycemic state

Topic: Medical-surgical

A life-threatening hyperglycemic crisis, mainly in older adults with type 2 diabetes, in which there is enough insulin to prevent ketoacidosis but not to control glucose. 2024 consensus criteria include glucose of 600 mg/dL or more and an effective serum osmolality above 300 mOsm/kg without significant ketonemia or acidosis. It develops over days, often after infection or poor fluid intake, and causes profound dehydration and confusion, seizures or coma. Treatment starts with IV fluids, then insulin; monitor neurological status, glucose, osmolality, potassium, and intake and output.

Also known as:
HHS, Hyperosmolar hyperglycemic nonketotic syndrome, HHNS

What does Hyperosmolar hyperglycemic state mean?

Hyperosmolar hyperglycemic state is part of the Medical-surgical topic in nursing. Students meet it in class, on clinical placements and while preparing for exams.

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